Aditya Anand About Research Publications Media Creative Advice

Publications

Selected Publications

  1. Anand AA, et al. Context-dependent principles of endosomal escape from cross-dataset CRISPR screen analysis. In preparation (target: January 2026).
  2. Anand AA, et al. Proteomic mapping of gut pathogen effectors reveals epithelial defense pathways subverted by Shigella and pathogenic E. coli. In preparation (target: Spring 2026).
  3. Capietto A-H, Balança CC, Bouzair R, Wu TD, Gober J, Carbone C, Anand AA, et al. (2025). A single MHCII neoepitope mRNA vaccine elicits CD4 T- and B-cell responses promoting endogenous CD8 anti-tumor immunity. bioRxiv.
  4. Carbone CB, Brown M, Balança CC, Antonelli AC, Luoh SM, Banta KL, Anand AA, et al. (2025). Intratumoral cDC1-T cell clusters serve as sites of local costimulation to enhance CTL-mediated tumor rejection. bioRxiv.
  5. Lawrence RE, Shoemaker SR, Deal A, Sangwan S, Anand AA, et al. (2024). A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nature Chemical Biology 20, 422–431.
  6. Anand AA, Walter P. (2020). Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response. The FEBS Journal 287, 239–245.
  7. Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Anand AA, et al. (2020). An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science 370, 1473–1479.
  8. Rabouw HH, Visser LJ, Passchier TC, Langereis MA, Liu F, Giansanti P, Anand AA, et al. (2020). Inhibition of the integrated stress response by viral proteins that block p-eIF2–eIF2B association. Nature Microbiology 5, 1361–1373.
  9. Anand AA, Kenner LR, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A. (2019). eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Science 364, 491–495.
  10. Rabouw HH, Langereis MA, Anand AA, et al. (2019). Small molecule ISRIB suppresses the integrated stress response within a defined window of activation. PNAS 116, 2097–2102.
  11. Tsai JC, Miller-Vedam LE, Anand AA, et al. (2018). Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Science 359, eaao939.
  12. Williams GJ, SilDas S, Anand AA, et al. (2015). Structural insights into the RAD51 paralog complexes reveal molecular details of disease causing mutations. Journal of Biomolecular Structure and Dynamics 33, 137–137.